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Future clinical trials should be performed in much larger patient cohorts with attention to the longer-term outcomes and safety profile of L-carnitine supplementation over prolonged periods

3 Additionally, neuronal vulnerability in PD extends beyond the nigrostriatal pathway and includes specific neurons in autonomic ganglia, basal ganglia, spinal cord, and neocortex

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Some reports indicate that amelioration of metabolic profiling by gastrectomy was associated with autophagy induction (Soussi et al., 2016)

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