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Towards a more precise diagnosis of hypersensitivity to beta-lactams an EAACI position paper

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For testing on a first-time melanotan II subject, it is important to start with the lowest dose possible, before increasing as needed to achieve the desired outcome

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doi: 10.3389/fonc.2025.1576781 Received 14 February 2025 Accepted 16 June 2025 Published 27 June 2025 Volume 15 - 2025 Edited by Sandip Patil, Shenzhen Childrens Hospital, China Reviewed by Francesco Grignani, University of Perugia, Italy Barbara A Osborne, University of Massachusetts Amherst, United States Katia Carneiro, Federal University of Rio de Janeiro, Brazil Madduri Srinivasarao, Purdue University, United States Updates Copyright 2025 Tian, Han, Song, Liu, Shen and Zhong

GIP Receptor Activation: Insulinotropic Action: Stimulation of GIP receptors augments insulin secretion in response to nutrient ingestion, working synergistically with GLP-1 to improve overall glucose homeostasis