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2007: A study in 36 people (average age 63) with coronary artery disease found that taking 500 mg of acetyl-L-carnitine plus 200 mg of alpha-lipoic acid twice daily for 8 weeks lowered systolic blood pressure by 9 mmHg in those with coronary artery disease and high blood pressure, which was significant compared to placebo

However, because of its lipophilic structure and sluggish penetration rate, lipohydroxy acid can exfoliate dead skin cells from the skin's outer layer more thoroughly, virtually mirroring our natural desquamation (skin shedding)

Those brand-name finished drug products went through full FDA review for safety, effectiveness, quality, and manufacturing consistency

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Binienda Z, Przybyla-Zawislak B, Virmani A, Schmued L (2005) L-carnitine and neuroprotection in the animal model of mitochondrial dysfunction

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