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IGF-1 levels are not meaningfully affected a distinguishing feature from full hGH

The pathogenesis of CIPN is multifactorial, involving oxidative stress, neuroinflammation, neurotrophic factor depletion, and mitochondrial dysfunction (610)

Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network

Since the pKa of Sec is ~ 5.2, the selenol (RSeH) of Sec exits in selenolate (RSe ) form under the physiological condition [8, 11,12,13,14,15,16,17,18]

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