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In each of these, mast cell activation appears to play a role in symptom severity, barrier dysfunction, and disease progression

BACKGROUND OF THE INVENTION Field of the Invention (Technical Field): The present invention relates to a method and multiple agents for treatment of sexual dysfunction, including male erectile dysfunction, including separate and preferably sequential administration of a melanocortin 3 and/or 4 receptor agonist, such as Ac-Nle-cyc/o(-Asp-His-D-Phe- Arg-Trp-Lys)-OH (PT-141), preferably by one route of administration, such as intranasal (IN), and a type V phosphodiesterase (PDE-5) inhibitor, such as Viagra , a trademark for a brand of sildenafil, preferably by another route of administration, such as oral

I've seen that a couple of times

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Prompt evaluation by an ophthalmologist can determine if NAION or another eye condition is present