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ROS in cancer therapy: the bright side of the moon

Worsening intracellular oxidative potential was accompanied by increases in intracellular expression of downstream T2 signature proteins, such as POSTN and CCL26, with nonsignificant increases in inducible NO synthase (iNOS/NOS2

Similarly, severe heart failure or pulmonary edema represents a contraindication or strong precaution, as large amounts of glycine solution may expand intravascular volume and precipitate or worsen congestive heart failure or pulmonary congestion