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C), 38.77 (CH 2 ), 38.35 (CH 2 ), 27.50 (CH 2 ), 26.84 (d, J = 16.7 Hz, CH 2 ), 22.37 (d, J = 51.3 Hz, CH 2 ), 21.77 (d, J = 4.3 Hz, CH 2 )

doi: 10.1016/j.biopha.2019.109249 22 ZiaAFarkhondehTPourbagher-ShahriAMSamarghandianS

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In some embodiments, the otic formulation or composition comprises between about 1% to about 2% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof