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Prior to that, the treatment of obesity has been predominantly limited to lifestyle interventions and bariatric surgery

Comorbidities such as high blood pressure, high cholesterol, rheumatoid arthritis, or cardiovascular diseases can lead to respiratory system symptoms

Front Pharmacol (2016) 7:385

Lactate shuttling and lactate use as fuel after traumatic brain injury: metabolic considerations

For type 2 diabetes, NICE recommends continuing GLP-1 therapy only if HbA1c falls by 11 mmol/mol AND body weight reduces by 3% at 6 months

It is also of interest in aging research for its ability to reduce all-cause mortality in mouse models and prolong lifespan