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For many, there are effective and less invasive options

That means no increase in IGF-1 production, no effect on blood glucose, no insulin resistance, no water retention, and no risk of the organ growth associated with full HGH therapy

They posit its potential role in boosting dermal cell multiplication and survival, both of which are essential in collagen production

Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects

The two are at different levels of evidence, which is something to be aware of in practical considerations

PMID: 32257855