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Unlike systems that generate entire pathways in a single pass, DeepRetro employs an iterative refinement loop where each LLM-proposed step undergoes rigorous validation for chemical soundness, stability, and plausibility before being accepted
[3] This is an animal study, so it demonstrates how probiotics can raise GLP-1 rather than proving a specific weight-loss result in people, but it establishes the pathway cleanly: more of the right bacteria means more butyrate, and more butyrate means more GLP-1
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