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The Problem of Over-Basalization Uptitrating basal insulin is no longer having an HbA1c-lowering effect, while higher insulin doses mean greater risk of weight gain and hypoglycemia

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Intriguingly, we observed a 30% increase in glycolysis and a 33% increase in mitochondrial glucose oxidation in MTP siRNA versus control siRNAtreated cells (ECAR: 6.2 0.1 vs

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