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Journal of Biological Chemistry, 275, 1263312638

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Li, N., Walln, N.H., Ladjevardi, M

A 2019 trial published in the British Journal of Dermatology demonstrated that afamelanotide without controlled UV exposure produced zero measurable change in skin pigmentation across 60 days

This is significant, as cardiovascular disease is one of the leading causes of death in people with diabetes

However, they also come with potential drawbacks like allergic responses, risk of low blood sugar (hypoglycemia), and the safety of usage during pregnancy is not well established