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These are unstable molecules that can cause oxidative stress, a process similar to biological "rusting" that damages cells over time

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Traditional Chinese medicine network pharmacology: theory, methodology and application

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Ndisang JF

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For oral administration in mice, NR and NMN are first metabolized by the liver or GI tract into NAM, which can then be taken up by other tissues

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The animals were fed either a standard chow diet (Harlan TD.08485, providing 5.2% calories as fat

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