Since the first patient with skin cancer was cured by radiotherapy in the late 19th century 6,7 , radiotherapy has continuously evolved and remains an essential modality with established therapeutic benefits across multiple malignancies, including lung 8 , oesophageal 9 , rectal 10 , and cervical cancers 11
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Concurrently, an observed surge in growth hormone levels, which typically accompanies muscle resistance, may add complexity to this molecular interplay
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