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Dose escalation is stopped when pre-defined exposure or toxicity thresholds are reached

ALA exhibits a high degree of plasma protein binding, primarily to albumin, which affects its distribution and bioavailability

DOI: 10.1021/bi400405p 26

Das TK, Wati MR, Fatima-Shad K (2015) Oxidative stress gated by Fenton and Haber Weiss reactions and its association with Alzheimers disease

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