Proof of Past Failures: This is critical
There is no FDA-approved adult or athletic indication for any IGF-1 product
Start with a low dose and gradually increase as needed, up to a maximum of around 2 grams per day
Subiran N, Agirregoitia E, Valdivia A, Ochoa C, Casis L, Irazusta J
Importantly, circulating HTY metabolites, mainly HTY sulfate and HTY glucuronides, reach plasma concentrations several-fold higher than parent HTY and retain cardiovascular-related bioactivity
The model is also consistent with published results that show that female mice are less susceptible than males to hepatotoxicity due to acetaminophen overdose and suggests that this might also be true for humans, though the human epidemiological data are contradictory