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International Journal of Molecular Sciences, 23 (3), 1445

Mitochondria play a central role in APAP-induced cell death and injury and therefore greater knowledge about the relationship between mitochondria with other organelles such as lysosomes can result in improved future therapeutic options for APAP-induced liver injury

We characterized the genes encoding for glutathione biosynthetic enzymes, glutathione reductase ( glr ), glutathione peroxidase ( gpx ) and glutathione S-transferases ( gsts )

Upon baicalin pre-treatment, LPS induced BV-2 microglia expression of NO, iNOS, IL-1, PGE2, ROS, IL-6, TNF-, COX-2 decreased and TLR4/NF-B pathway activation was reduced (Yan et al., 2020

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