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It is also distinct from dose reduction after reaching maintenance

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On the Pleiotropic Actions of Glucagon-like Peptide-1 in Its Regulation of Homeostatic and Hedonic Feeding

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With a mean follow-up of 2.6 years, the study demonstrated a 34% reduction in the relative risk (RR) of a composite renal outcome, including dialysis requirement, a decline in glomerular filtration rate (GFR) 7% were initiated on the complementary drug to complete the GLP-1 RA + SGLT-2i combination therapy

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