The vitiligo patients were further divided into two treatment groups: 15 patients in the topical steroids-only group and six in the combination therapy group, which includes phototherapy and topical steroids
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Two CD95 (APO-1/Fas) signaling pathways
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Composed of 15 amino acids, this pentadecapeptide has been shown in research to stimulate angiogenesis, collagen formation, and tissue remodeling.- It may interact with nitric oxide pathways, growth factor expression, and inflammatory cascades to support endothelial function and cellular recovery.- Suggested mechanisms include upregulation of VEGF, engagement with FAK-paxillin signaling, and protective effects under oxidative stress conditions
On the other hand, Ab-CLP group maintained normal hematological parameters compared to sham group (Figures 2CF)