Modified Irvine, Beatties and Bresnahan forelimb scale (IBB scale, scored 02, 03, 01) (63, 64) for assessment of forelimb function impairment in rats that received cuprizone diet, and then cuprizone intragastrical applications, and thereby, cuprizone toxicity manifestations
The primary outcome of this trial was the percentage of patients with incident LIDs by month 18 and showed a statistically significant difference in favor of amantadine (11% vs 22% on placebo
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