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There are five types of melanocortin receptors, MC1R, MC@R, MC3R, MC4R and MC5R

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Cancer promotion occurs because an elevated ROS level does the following: (a) facilitates tumorigenesis through damaging or modifying cellular proteins, DNA, and lipids, leading to activation or inhibition of various tumorigenesis related signaling cascades (Tafani et al., 2016)