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Initial fragment library screens for thiol reactivity and selectivity revealed that O-to-S exchange increases thiol-reactivity, while maintaining amino acid selectivity and aqueous stability

This superhero is glutathione, a naturally occurring antioxidant composed of three amino acids: cysteine, glycine, and glutamic acid

Although PZQ inflicted more damage, AS was more active than PZQ inducing more mortality among NTS (Additional file 1: Table S1), consistent with other reports that indicated that AS was more effective against larval and young stages of S

doi: 10.1016/S2213-8587(23)00356-X 81 ApovianCMMcDonnellME

Transaminase of branched chain amino acids