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More recently, a multiple hits theory has been proposed, with the addition of other pathogenic factors in NAFLD development: low-grade chronic inflammation, genetic and epigenetic mutations, and intestinal microbiota

The cystine/glutamate antiporter system x(c)(-) in health and disease: From molecular mechanisms to novel therapeutic opportunities

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Following stroke, neurons in the ischemic core undergo irreversible death within minutes, whereas those in the surrounding penumbra progressively degenerate over the subsequent hours to days (Fifield & Vanderluit, 2020)

It also helps recycle other antioxidants, like Vitamin C and Vitamin E, making them more effective