dulaglutide vs semaglutide for weight loss Comparative effectiveness of and combined with hypocaloric diet in newly diagnosed type 2 diabetes: a retrospective real-world study | BMC Endocrine Disorders Dulaglutide vs. Semaglutide For Weight

Cardiovascular benefits have been demonstrated in clinical trials, with specific agents showing reductions in major adverse cardiovascular events

Your doctor may recommend spacing out the time when you take each medication to lessen the chances of gastrointestinal issues

If necessary, the dose may be increased to 1 mg or 2 mg weekly after at least 4 weeks at each dose level

Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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Diabetologia 65:19251966 Ahmann AJ, Capehorn M, Charpentier G, Dotta F, Henkel E, Lingvay I, Holst AG, Annett MP, Aroda VR (2018) Efficacy and safety of once-weekly semaglutide versus exenatide ER in subjects with type 2 diabetes (SUSTAIN 3): a 56-week, open-label