Ridha Z et al, Aesthetic Surgery Journal 44(11):NP809-NP818, PMID 38874170) describes GLP-1 receptors on adipose-derived stem cells (ADSCs) and fibroblasts in skin, and proposes that activation of these receptors may reduce protective cytokine production from ADSCs, increase oxidative stress on neighboring fibroblasts, reduce ATP production through altered glucose uptake, and indirectly reduce local estrogen production from dermal white adipose tissue
Histological clarification
(We will have to talk another time about using handgrip as an outcome)
By simultaneously pushing the accelerator via GHRH receptors and removing the brakes via somatostatin inhibition, the resulting pulse is significantly more potent than either peptide could produce in isolation
Until then, a tailored and collaborative approach remains the cornerstone of effective obesity management
(2) Raun K, Hansen BS, Johansen NL, Thgersen H, Madsen K, Ankersen M, Andersen PH