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Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2 trial (Lancet Diabetes & Endocrinology)

The exploration of macrocycles for drug discoveryan underexploited structural class

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Russian clinical trials have contributed valuable data, but methodological differences, including smaller sample sizes, different statistical approaches, and less rigorous blinding procedures compared to FDA standards, mean that Western regulatory agencies generally do not accept this data for drug approval

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