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The cost of a replacement vial is less than the cost of injecting degraded peptide that does not work or causes unexpected reactions

The clinical trial protocol used a gradual dose escalation to minimize GI side effects: Most users inject into the abdominal area, rotating sites with each injection

10.1073/pnas.0809222105 419 MittagT.MarshJ.GrishaevA.OrlickyS.LinH.SicheriF.et al (2010)

Vial puncture frequency directly correlates with contamination risk

Therefore, it allows a vial to be used multiple times while maintaining sterility unlike standard sterile water for injection, which is typically single-use only

Wine is fermented and is often very high in biogenic amines, including histamine