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5d), indicative of their potential usage in PD care

Although the negative studies obtained with the MAO-B inhibitor selegiline (deprenyl) and the antioxidant tocopherol (vitamin E) may have resulted from an inappropriate choice of drug (selegiline) or an inadequate dose (tocopherol), the niggling problem that still remains is why these drugs, and others, do work in animals while they fail in the clinic

Additional examples of otoprotectants include, but are not limited to, Hes1/Hes5 SiRNA, Hes1 SiRNA, Hes5 SiRNA or other comparable modulators

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