Most ALA supplements contain a racemic mixture, meaning they include both the R- and S- forms of alpha-lipoic acid in equal amounts
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Methods This literature screening was conducted based on the PubMed, Web of Science, and CNKI databases, with the search timeframe spanning from January 2010 to May 2025
It then interacts with nuclear transcription factors like GATA-4 and MEF2, upregulating the transcription of CH-related genes (222, 223)
In the Lurcher mutant cerebellum, also inconstant changes in trophic factor levels [103, 114, 115], significant changes in the vascular bed [68], changes in inflammatory cytokines [116] and immune cell and organ abnormalities [117, 118] have been found
