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MC dendricity and cell area Epifluorescence micrographs of actin (phalloidin staining) or td-Tomato, for pMCs and iMCs, respectively, were preprocessed using a mean filter to smoothen images, by reducing noise and averaging pixel values, followed by the median filter, which further reduced noise while preserving edges and details
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In contrast, the most recent studies have shown an increase in tumor development and metastasis in mouse models treated with vitamin E 155 (an opposite result of that in which high doses of vitamin C increase ROS levels to induce the death of colon cancer cells bearing KRAS and BRAF mutations) 156
