Evidence specific to athletic or bodybuilding use in healthy young adults remains limited and largely anecdotal rather than drawn from controlled human trials
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Family history and certain genes may increase susceptibility to the disorder, while stress and infections have been identified as potential triggers
Elmiron, a drug prescribed for interstitial cystitis, has been linked to serious eye damage and vision problems in scientific studies
Postmortem analyses of Alzheimers disease brain tissue reveal abnormal aquaporin-4 expression and mislocalization, supporting a bidirectional relationship between impaired glymphatic clearance and A accumulation that accelerates brain aging and cellular degeneration (Zeppenfeld et al., 2017
Some people splitting into 2x/week report fewer GI sides, but it's not required