Evidence supporting the involvement of activated microglia-mediated chronic neuroinflammation in PD includes: (1) Pro-inflammatory effects are often observed in activated microglia surrounding dopaminergic neurons, with the degree of microglial activation correlating with dopaminergic endings loss in PD (174, 175)
Attention to the side effects of these drugs has focused on gastrointestinal symptoms, but bone health is an area where research is still early and conflicting
Gastroenterology 123(5):160715
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3) Common pathophysiological mechanisms involving impaired SCFA production, immune-inflammatory activation, and dysregulated neuroactive metabolite metabolism
Feeding skills: Evaluation of oral-motor deficits such as weak suck, tongue thrust, poor lip closure, and oral tactile sensitivity is of paramount importance