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Alarcon de la Lastra 2001)

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Extremely high plasma glycine concentrations may lead to hyperglycinemia and, via catabolism, hyperammonemia, potentially causing neurological symptoms such as headache or confusion-though such events are exceedingly rare outside massive irrigant absorption

Bremelanotide reduced survivin expression and induced cell death in glioblastoma cells at concentrations that were not toxic to normal human cells

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Many people think these medications are brand-new to the market, but the FDA actually approved the first GLP-1 agonist (exenatide, branded as Byetta) in 2005