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Use day & night after cleansing and before moisturiser

GIP is also a peptide hormone composed of 42 amino acids that is synthesized and secreted mainly by enteroendocrine K cells in the duodenum and proximal jejunum 39,40

Several mechanisms have recently been proposed to explain the augmented OS during obesity, including altered glucose and lipid homeostasis, systemic inflammation, hyperleptinemia, and abnormal postprandial ROS production (122)

Ongoing TRIUMPH trials include weight maintenance arms that will address this, though results aren't expected until 2027 or later

He notes that obesity has long been associated with poor COVID-19 outcomes due to fat cells being particularly receptive to the virus