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Conclusion Diabetes and its complications remain a global burden, causing a significant increase in mortality and morbidity each year, as reported by WHOs health statistics

Moreover, the initial model of CTR: Cagri/CagNN in the bypass conformation was generated from AMY 1 R:Cagri by removal of RAMP1

ZOs are peripherally associated proteins that interact with claudins, occludins, and JAMs to anchor the membrane proteins, tethering them to the actin cytoskeleton [10, 16]

Opting for skin whitening treatments is a personal choice, but its safety is still questionable[1]