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The results were significant: At 48 weeks, participants receiving the 12 mg dose achieved a mean weight reduction of 24.2% (approximately 58 pounds or 26.2 kg) 100% of participants on the 8 mg or 12 mg doses lost at least 5% of their body weight More than 90% of participants on the 12 mg dose lost at least 10% of their body weight Nearly half of participants on the highest dose lost 25% or more of their body weight The study also showed improvements in cardiometabolic markers including blood pressure, triglycerides, LDL cholesterol, and fasting glucose

doi:10.2174/157015913666160502153022

Also, it is one of the most difficult vitamins to absorb, and it requires normal function of the stomach, pancreas and small intestine

Physician supervision ensures that any unexpected response is identified and managed promptly

In contrast, fat-soluble vitamins can remain in the body for longer, sometimes up to several months

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