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However, the same theoretical concerns regarding chemotherapy agents apply [2][5]

Thakur M, Kumar I, Dhiman S (2023) A review on Artemisia princeps: pharmacology and anti-inflammatory potential of phytoconstituents

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Duperray, J., Sergheraert, R., Chalothorn, K., Tachalerdmanee, P., & Perin, F

In general, it is assumed that the two main limiting factors are the levels of cysteine and of the enzyme gamma-glutamyl-cysteine synthetase (also known as glutamate-cysteine ligase)

Low levels of glutathione are also associated with chronic exposure to chemical toxins and alcohol, cadmium exposure, smoking, AIDS/HIV, macular degeneration, Parkinsons disease, and other neurodegenerative disorders