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Some common side effects include: Nausea Vomiting Diarrhea Constipation Abdominal pain While less common, some patients using Semaglutide may experience more serious side effects: Hypoglycemia: Combining Semaglutide with insulin or sulfonylureas can increase the risk of low blood sugar

US Department of Health and Human Services

Semaglutide vs Tirzepatide Although manufacturers emphasise differences between products, the TUM study shows only minor distinctions in cardiovascular outcomes between Semaglutide and Tirzepatide

In 2025, the World Health Organisation added semaglutide and other GLP-1 medicines to its Model List of Essential Medicines for selected patients with type 2 diabetes who also have cardiovascular disease, chronic kidney disease or obesity

Mounjaro, meanwhile, is still undergoing research, and its precise properties and applications are yet to be fully defined

What are the signs of a semaglutide side effect