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( Placebo-Controlled Studies With DPP-4 Inhibition as Add-on to Ongoing Thiazolidinedione Therapy When added to on-going therapy with a thiazolidinedione in subjects with type 2 diabetes, the DPP-4 inhibitors were studied in 2426 week placebo-controlled studies with a total number of 2,146 subjects [Table 2

PMID 7961718

Hyperplastic oval cells occur in association with a high incidence of hepatocellular neoplasms and may play an important role in hepatocarcinogenesis

PubMed Fletcher, M.M., Halls, M.L., Christopoulos, A., Sexton, P.M., & Wootten, D

This compound is not approved for human therapeutic use