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The 7.2 mg dose could provide additional benefits for patients who require a higher magnitude of body weight loss, and stratification of patients who could benefit from the higher dose will play a large role in the management of obesity, Wharton and colleagues wrote

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This mechanism supports your weight loss journey but can cause constipation as food moves more slowly through your digestive system

Your doctor will need to develop a safe and effective transition plan for you

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A competent prescriber understands obesity as a disease, the full medication toolkit, the controlled-substance compliance phentermine requires, the side-effect and lean-mass considerations semaglutide brings, and the program-level judgment that decides when to use one, the other, or both in sequence