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Systematic Review Registration: identifier CRD42024602837

Presence of the enzyme and induction by oxidative conditions

It is highly expressed in the hypothalamus, where it plays a crucial role in the regulation of protein trafficking and recycling, which affect secretory granule biogenesis ( MAGEL2 cause Schaaf-Yang syndrome (MIM: 615547), which is characterized by delayed psychomotor development, frequent intellectual disability, hypotonia, feeding difficulties, and various dysmorphic facial features

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Modulation of glutathione and its related enzymes in plants responses to toxic metals and metalloidsA review