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Since fat builds up in the liver, it only decreases the bodys metabolic rate, making it impossible to lose weight even with a balanced diet and exercise
Recently, GPx4 was predicted to be a specific target for new pharmacological therapies aimed at activating or inhibiting cell death in cancer or degenerative diseases [110]
Glutathione homeostasis and functions: potential targets for medical interventions
Moreover, overexpression of specific GSTs can also affect chemoresistance, whereas polymorphisms that decrease GST activity are associated with a high risk of developing cancer [72]