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Yamada, Hideto, et al

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In contrast, benign liver tumor development has been demonstrated in systematic mosaic Atg5 KO/KO and liverspecific Atg7 KO/KO mice ( Thyroid cancers developed in Braf thyrV600E , Braf thyrV600E ,Atg5 thyrKO/KO , and Braf thyrV600E ,Mieap KO/KO mice are similar in terms of the degree of cell proliferation and differentiated status, but tumor sizes and ROS levels indicated by 53BP1 foci were the highest in Braf thyrV600E ,Mieap KO/KO mice