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doi: 10.1038/s44259-024-00046-3 [DOI] [PMC free article] [PubMed] [Google Scholar] 37.Urun C, Chopo-Escuin G, Tommassen J, Mainar-Jaime RC, Arenas J

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systematic review highlighted concerns regarding the quality of studies on the prevention or treatment of fracture non-union, pinpointing issues like lack of method standardization, inconsistent outcome measures, and inadequate reporting, which currently hampers the feasibility of meta-analyses [4]

We recently identified the FOXO4 p53 axis as pivotal in maintaining the viability of senescent cells, and that senescent cells can be targeted selectively with the senolytic peptide FOXO4-DRI

Timing right