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A lack of glutathione has been associated with neurodegenerative diseases, pulmonary diseases, immune diseases, cardiovascular diseases, chronic age-related diseases, liver disease, cystic fibrosis, and the aging process itself

& Verkhusha, V

PLoS ONE 7 , e33284 (2012)

Reference total RNA from human liver was obtained from Invitrogen

Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

Other chronic conditions such as malabsorption, Fanconi syndrome, diabetes mellitus, heart failure and Alzheimer's disease have also been associated with carnitine deficiency