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Longitudinal data were analyzed by two-way ANOVA followed by Tukey post hoc analysis ( db / db glucose and DIO mouse data) or two-way ANOVA followed by Sidak or Bonferroni post hoc analysis (HFHF canine acute oral glucose tolerance test data and 14-day data)

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Researchers should consult primary literature (PubMed, Google Scholar) before designing experiments and confirm dose-ranges, vehicle compatibility, and analytical methods against the published methodology

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