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5 Progress in research on clinical intervention strategies Table 2 summarizes key intervention strategies and their mechanisms, helping to provide a clearer understanding of how each strategy targets ferroptosis and its potential application in cardiovascular diseases and other related conditions ( Table 2 Clinical intervention strategies for ferroptosis

Laakso M, Zilinskaite J, Hansen T, Boesgaard TW, Vanttinen M, Stancakova A, et al

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Mitochondrial dysfunction and structural changes in ferroptosis Ferroptosis is distinguished from other forms of regulated cell death by its characteristic mitochondrial morphology

However, the response to ICIs is heterogeneous, and biomarkers like PD-L1 expression levels have been correlated with treatment outcomes

JAMA 293 , 16441652 (2005)