Low IGF-1 Frailty, sarcopenia, poor wound healing, lower bone density
Extending beyond 12 weeks requires reassessment if weight loss has plateaued despite adherence to diet and activity, the limiting factor is metabolic adaptation or dietary structure, not insufficient lipotropic support
INDICATIONS Invigorating and restorative of the body prior to rigorous physical activity such as training, competition and exhibition
Therefore, diabetic patients with acromegaly could be treated with SGLT-2i, albeit caution is required for patients with uncontrolled disease
Other brain regions with GLP-1 receptor expression include: Ventral tegmental area and nucleus accumbens (reward and motivation circuits) Amygdala (emotional processing and stress responses) Prefrontal cortex (executive function and decision-making) Substantia nigra (motor control, relevant to Parkinson's disease research) This widespread distribution suggests that GLP-1 influences diverse neurological functions beyond appetite regulation
Follow-up appointments are available virtually for established patients