These are promising results, but the studys authors note that more research is needed, and clinicians must also consider potential adverse effects, evaluate the cost-effectiveness of these medications for each patient, and closely monitor for any improvement or worsening of eating disorders and related side effects. That hesitation is shared by the National Eating Disorder Association (NEDA), who published an opinion paper on GLP-1s and eating disorders in 2024, stating: While there is some evidence that GLP-1s can decrease the number of binge eating episodes for those with BED, little is known about the long term physical and psychological impact on those with eating disorders. How GLP-1s could also fuel eating disorders The same mechanisms that make these medications helpful for some could make them harmful for others
In general, evidence has shown that inhibition of the NO generation prevents inhibition of sympathetic vasoconstriction in the skeletal muscle in contracted or rested forms in humans and rodents (103)
But before you rush out and buy a glutathione supplement, heres something critical: not all glutathione is created equal
Glutathione: The Master Detoxifier Glutathione is one of the most powerful antioxidants
For a moderate dose of 250mcg, a 10mg (10,000mcg) vial contains 40 doses
In contrast, lacosamide blocks the slow inactivation state, which may explain the added benefit of lacosamide in combination with carbamazepine
