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(2022) showed LEO pretreatment could alleviate ischemic AKI by promoting Nrf2 nuclear translocation, which counteracts OS injury and inhibits TLR4/NF-B pathway that mediates inflammatory expression

When the amount of tyrosinase is reduced, the melanin formation process is also prevented, leading to brighter skin and less darkening

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In conclusion, our data suggest that GSSG is a potent and clinically relevant sensitizer for TNF-induced hepatotoxicity in NAFLD, which represents a potential therapeutic target for NAFLD

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